huagongshe.com
HRID852052

反应详情

EQUATION

反应方程式

HRID 852052 的结构方程式

REACTANTS

反应物

3
结构：O=[N+]([O-])c1c(Cl)ncnc1Cl
HCID20312

4,6-Dichloro-5-nitropyrimidine

C4HCl2N3O2

结构：CCN(C(C)C)C(C)C
HCID81531

Diisopropylethylamine

C8H19N

结构：CNCC(C)(C)C.Cl
HCID22393520

N,2,2-Trimethylpropan-1-amine--hydrogen chloride (1/1)

C6H16ClN

PRODUCTS

生成物

1
结构：CN(CC(C)(C)C)c1ncnc(Cl)c1[N+](=O)[O-]
HCID58928507

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(C)=O
溶剂HCID180

Acetone

C3H6O

PROCEDURE

实验过程

4,6-Dichloro-5-nitro-pyrimidine (0.20 g, 1.0 mmol), N-methyl-neopentylamine hydrochloride (0.14 g) and DIEA (0.2 mL) were stirred in acetone (5 mL) at 0° C. for 4 hours. The solvent was removed in vacuo and the crude product was used for the next reaction without purification.

WORKUP

后处理

  1. customThe solvent was removed in vacuo
  2. customthe crude product was used for the next reaction without purification