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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 852167Generated: October 31, 2026

Dimethylformamide → HCID 58928275, compound

https://huagongshe.com/reaction/852167

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
Reactant(R)-6-fluoro-3-(4-oxiranylmethoxy-phenyl)-benzo[d]isoxazoleHCID 58928269—
SolventEthanolHCID 702—
Solvent2-(1-Cyclohexenyl)ethylamineHCID 76938—
ProductHCID 58928275HCID 58928275—

Reaction Steps

The title compound is prepared from a mixture of (R)-6-fluoro-3-(4-oxiranylmethoxy-phenyl)-benzo[d]isoxazole in dimethylformamide and 2-(1-cyclohexenyl)ethylamine in ethanol, essentially as described above in Example 70. Purity by LC/MS=100%, [M+H]+=411.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07253165B2
Source datasetuspto-grants-2007_08
ORD IDord-89f7447c4d7649f1a9ae801c642e4e5a
Source noteuspto-grants-2007_08