HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1S,2R)-(-)-1-Amino-2-indanol → HCID 69416792, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1S,2R)-(-)-1-Amino-2-indanol | HCID 9866743 | — |
| Reactant | (R)-6-fluoro-3-(4-oxiranylmethoxy-phenyl)-benzo[d]isoxazole | HCID 58928269 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 69416792 | HCID 69416792 | — |
Reaction Steps
The title compound is prepared from a mixture of (R)-6-fluoro-3-(4-oxiranylmethoxy-phenyl)-benzo[d]isoxazole in dimethylformamide and (1S, 2R)-(−)-cis-1-amino-2-indanol in ethanol, essentially as described above in Example 70. Purity by LC/MS=100%, [M+H]+=435.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07253165B2 |
| Source dataset | uspto-grants-2007_08 |
| ORD ID | ord-298e3a2bc64848bfaa3da9755f627f39 |
| Source note | uspto-grants-2007_08 |