Potassium Carbonate → HCID 9907854, compound

HRID 852201Notes

Reaction equation

HRID 852201 reaction equation
Br[CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[C:13]3[CH:20]=[CH:19][CH:18]=[CH:17][C:14]=3[S:15][CH:16]=2)=[CH:8][CH:7]=1.[S:21]1[CH:25]=[CH:24][CH:23]=[C:22]1[CH2:26][NH2:27].C(=O)([O-])[O-].[K+].[K+]>C(#N)C>[S:15]1[CH:16]=[C:12]([C:9]2[CH:10]=[CH:11][C:6]([O:5][CH2:4][CH2:3][CH2:2][NH:27][CH2:26][C:22]3[S:21][CH:25]=[CH:24][CH:23]=3)=[CH:7][CH:8]=2)[C:13]2[CH:20]=[CH:19][CH:18]=[CH:17][C:14]1=2

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 34005(2-Thienylmethyl)amineHCID 179063143-[4-(3-Bromo-propoxy)-phenyl]-benzo[b]thiophene

Product 1

HCID 9907854HCID 9907854, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

The title compound is prepared from 3-[4-(3-bromo-propoxy)-phenyl]-benzo[b]thiophene, 2-thiophenemethylamine, potassium carbonate and acetonitrile essentially as described above in Example 118. Purity by LC/MS=97%, [M+H]+=380.

Sources & evidence

ORD record
ord-fc7d341f39a64b3a9753d99a64614747
Source dataset
uspto-grants-2007_08
Patent number
US07253165B2

Reaction notes

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