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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 852236Generated: October 30, 2026

2-Nitrobenzenesulfonyl chloride → 2-(4-methylpiperazine-1-sulfonyl)phenylamine

https://huagongshe.com/reaction/852236

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Nitrobenzenesulfonyl chlorideHCID 15540—
Reactant1-MethylpiperazineHCID 53167—
Product2-(4-methylpiperazine-1-sulfonyl)phenylamineHCID 113281580%

Reaction Steps

The title compound (2.1 g, 80%) was obtained as a white solid from N-methylpiperazine and 2-nitrobenzenesulfonyl chloride following the same procedure as described in Preparation 2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07253171B2
Source datasetuspto-grants-2007_08
ORD IDord-bc043e2516f14b749b287af20dee50c7
Source noteuspto-grants-2007_08