反应详情

(S)-2-tert-Butoxycarbonylamino-3-[4-(3-cyano[1,6]naphthyridin-2-ylamino)phenyl]propionic acid methyl ester (0.12 g) was disolved in dioxane (2 ml) and treated with saturated solution of hydrogen chloride in dioxane (2 ml) for 2 h at room temperature. The solvent was removed under reduced pressure to yield the title compound (0.1 g, 96%) as a white solid.

1. customThe solvent was removed under reduced pressure