Hydrochloric Acid → HCID 69376868, compound

Participants

Reaction Steps

3 ml of a saturated solution of HCl in dioxane were added to a solution of (S)-2-tert-butoxycarbonylamino-3-(2′-cyano-biphenyl-4-yl) propionic acid methyl ester (513 mg, 1.35 mmol) in dioxane (4 ml) and the resulting mixture was stirred at room temperature for 3 h. The solvent was concentrated in vacuo to yield the title compound (425 mg, 99%) that was used in the next step without further purification.

Provenance & Evidence