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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 852263Generated: October 29, 2026

4-Aminophenol → HCID 57438531, compound

https://huagongshe.com/reaction/852263

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-AminophenolHCID 403—
Reactant2-Chloro-4-methoxypyridineHCID 1991128—
ReactantHCID 131726544HCID 131726544—
ProductHCID 57438531HCID 57438531—

Reaction Steps

4-Aminophenol was reacted with 4-methoxy-2-chloropyridine in the presence of KOtBu/18-Crown-6/DMA at 150° C. for 5 hrs to give 2-(4-aminophenoxy)-4-methoxypyridine. The product was purified by chromatography.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07253184B2
Source datasetuspto-grants-2007_08
ORD IDord-838e23abdcf642e493a9dd9a2fbc274b
Source noteuspto-grants-2007_08