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HRID852304

反应详情

EQUATION

反应方程式

HRID 852304 的结构方程式

REACTANTS

反应物

2
结构：CN(C)C(OC(C)(C)C)N(C)C
HCID79885

tert-Butoxy bis(dimethylamino)methane

C9H22N2O

结构：COCCC(=O)c1c[nH]c(C(=O)N[C@H](CO)c2ccccc2)c1
HCID60090604

未命名化合物

PRODUCTS

生成物

1
结构：COCC(=CN(C)C)C(=O)c1c[nH]c(C(=O)N[C@H](CO)c2ccccc2)c1
HCID86587976

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C1CCOC1
溶剂HCID8028

Tetrahydrofuran

C4H8O

PROCEDURE

实验过程

4-(3-Methoxy-propionyl)-1H-pyrrole-2-carboxylic acid (2-hydroxy-1-(S)-phenyl-ethyl)-amide was treated with an excess of Bredereck's reagent in THF at room temperature to 50° C. for 3 days. The solvent was removed under reduced pressure and the concentrate was used directly in the next step. HPLC Method B, Rt=5.0 minutes “broad peak”.

WORKUP

后处理

  1. customThe solvent was removed under reduced pressure