2-Pyridinecarboxaldehyde → HCID 9899550, compound
Reaction equation
Cl[C:2]1[CH:3]=[C:4]([N:8]2[N:12]=[N:11][C:10]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=3)=[N:9]2)[CH:5]=[CH:6][CH:7]=1.[F:19]C1C=CC(NC2C=CC=CC=2)=CC=1.N1C=CC=CC=1C=O>>[F:19][C:7]1[CH:6]=[CH:5][C:4]([N:8]2[N:12]=[N:11][C:10]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=3)=[N:9]2)=[CH:3][CH:2]=1Participants
4
Procedure
Following the procedure described in EXAMPLE 1 for the synthesis of 2-[2-(3-chlorophenyl)-2H-tetrazol-5-yl]pyridine, 4-fluorophenylaniline (33.3 mg, 0.3 mmol) and 2-pyridinecarboxaldehyde (32.1 mg, 0.3 mmol) were employed to obtain 2-[2-(4-fluorophenyl)-2H-tetrazol-5-yl]pyridine as an orange solid.
Sources & evidence
- ORD record
- ord-0e590f413ec4421c89f90b824a372f5f
- Source dataset
- uspto-grants-2007_08
- Patent number
- US07253190B2
Reaction notes
Loading…