2-Pyridinecarboxaldehyde → HCID 9899879, compound

HRID 852332Notes

Reaction equation

HRID 852332 reaction equation
ClC1C=C([N:8]2N=[N:11][C:10]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=3)=[N:9]2)C=CC=1.[NH2:19][C:20]1[C:21]([Cl:26])=[N:22][CH:23]=[CH:24][CH:25]=1.N1C=CC=CC=1C=O>>[Cl:26][C:21]1[C:20]([N:19]2[N:8]=[N:9][C:10]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=3)=[N:11]2)=[CH:25][CH:24]=[CH:23][N:22]=1

Participants

4

Reactant 3

HCID 142732-PyridinecarboxaldehydeHCID 805282-Chloro-3-pyridylamineHCID 99213692-[2-(3-chlorophenyl)-2H-tetrazol-5-yl]pyridine

Product 1

HCID 9899879HCID 9899879, compound

Procedure

Following the procedure described in EXAMPLE 1 for the synthesis of 2-[2-(3-chlorophenyl)-2H-tetrazol-5-yl]pyridine, 3-amino-2-chloropyridine (38.6 mg, 0.3 mmol) and 2-pyridinecarboxaldehyde (32.1 mg, 0.3 mmol) were employed to obtain 2-[2-(2-chloro-3-pyridyl)-2H-tetrazol-5-yl]pyridine as an orange solid.

Sources & evidence

ORD record
ord-d673c117e50548839261b9e3735b737f
Source dataset
uspto-grants-2007_08
Patent number
US07253190B2

Reaction notes

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