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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 852360Generated: October 30, 2026

2-(4-Acetylsulfanyl-2-methyl-phenoxy)-2-methyl-propionic acid ethyl ester → 2-Methyl-2-{2-methyl-4-[5-(3-trifluoromethoxy-phenyl)-pent-4-ynylsulfanyl]-phenoxy}-propionic acid ethyl ester

https://huagongshe.com/reaction/852360

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-Acetylsulfanyl-2-methyl-phenoxy)-2-methyl-propionic acid ethyl esterHCID 86597820—
ReactantMethanesulfonic acid 5-(3-trifluoromethoxy-phenyl)-pent-4-ynyl esterHCID 86602537—
Product2-Methyl-2-{2-methyl-4-[5-(3-trifluoromethoxy-phenyl)-pent-4-ynylsulfanyl]-phenoxy}-propionic acid ethyl esterHCID 69459160—

Reaction Steps

In analogy to the procedure described in example 1D], 2-(4-acetylsulfanyl-2-methyl-phenoxy)-2-methyl-propionic acid ethyl ester (example 1C]) was reacted with methanesulfonic acid 5-(3-trifluoromethoxy-phenyl)-pent-4-ynyl ester (example 3D]) to give 2-methyl-2-{2-methyl-4-[5-(3-trifluoromethoxy-phenyl)-pent-4-ynylsulfanyl]-phenoxy}-propionic acid ethyl ester as light brown oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07253192B2
Source datasetuspto-grants-2007_08
ORD IDord-9ae1ea31f7ff4cbf916c92c27fb5eca5
Source noteuspto-grants-2007_08