HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-2-(4-methylaminomethyl-phenoxy)-propionic acid ethyl ester → 2-Methyl-2-[4-({methyl-[5-(4-trifluoromethoxy-phenyl)-pent-4-ynoyl]-amino}-methyl)-phenoxy]-propionic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-2-(4-methylaminomethyl-phenoxy)-propionic acid ethyl ester | HCID 58907028 | — |
| Reactant | 4-Pentynoic acid, 5-[4-(trifluoromethoxy)phenyl]- | HCID 68822685 | — |
| Product | 2-Methyl-2-[4-({methyl-[5-(4-trifluoromethoxy-phenyl)-pent-4-ynoyl]-amino}-methyl)-phenoxy]-propionic acid ethyl ester | HCID 69459754 | — |
Reaction Steps
In analogy to the procedures described in example 29A], 2-methyl-2-(4-methylaminomethyl-phenoxy)-propionic acid ethyl ester was reacted with 5-(4-trifluoromethoxy-phenyl)-pent-4-ynoic acid (example 29D]) to give the title compound as light brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07253192B2 |
| Source dataset | uspto-grants-2007_08 |
| ORD ID | ord-0ae3d7135c9a4b7b9df13514b711e9b5 |
| Source note | uspto-grants-2007_08 |