HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanesulfonic acid 5-(4-trifluoromethoxy-phenyl)-pent-4-ynyl ester → 2-{3-Fluoro-2-methyl-4-[5-(4-trifluoromethoxy-phenyl)-pent-4-ynyloxy]-phenoxy}-2-methyl-propionic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanesulfonic acid 5-(4-trifluoromethoxy-phenyl)-pent-4-ynyl ester | HCID 11616756 | — |
| Reactant | 2-(3-Fluoro-4-hydroxy-2-methyl-phenoxy)-2-methyl-propionic acid ethyl ester | HCID 69460242 | — |
| Product | 2-{3-Fluoro-2-methyl-4-[5-(4-trifluoromethoxy-phenyl)-pent-4-ynyloxy]-phenoxy}-2-methyl-propionic acid ethyl ester | HCID 69457827 | — |
Reaction Steps
In analogy to the procedure described in example 20A], 2-(3-fluoro-4-hydroxy-2-methyl-phenoxy)-2-methyl-propionic acid ethyl ester (example 33H]) and methanesulfonic acid 5-(4-trifluoromethoxy-phenyl)-pent-4-ynyl ester (example 1G]) yielded the title compound as light yellow viscous oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07253192B2 |
| Source dataset | uspto-grants-2007_08 |
| ORD ID | ord-08315c49305b4b08ae0042051ebfea64 |
| Source note | uspto-grants-2007_08 |