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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 852413Generated: October 26, 2026

Propargyl bromide → 1-Prop-2-ynyl-cyclobutanecarboxylic acid ethyl ester

https://huagongshe.com/reaction/852413

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropargyl bromideHCID 7842—
ReactantEthyl cyclobutanecarboxylateHCID 84700—
Product1-Prop-2-ynyl-cyclobutanecarboxylic acid ethyl esterHCID 86602544—

Reaction Steps

In analogy to the procedure described in example 24C], reaction of ethyl cyclobutanecarboxylate and propargyl bromide gave the title compound as brown liquid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07253192B2
Source datasetuspto-grants-2007_08
ORD IDord-dcdd078e651c43ffb158f55122a445f5
Source noteuspto-grants-2007_08