2-Acetyl-3-methylpyrazine → HCID 23442631, compound

HRID 852435Notes

Reaction equation

[CH3:1][C:2]1[C:3]([C:8](=[O:10])[CH3:9])=[N:4][CH:5]=[CH:6][N:7]=1.[BrH:11].BrBr>>[BrH:11].[BrH:11].[Br:11][CH2:9][C:8]([C:3]1[C:2]([CH3:1])=[N:7][CH:6]=[CH:5][N:4]=1)=[O:10]

Participants

Reactant 2

HCID 320932-Acetyl-3-methylpyrazine

HCID 86584092HBr bromine

Product 1

HCID 23442631HCID 23442631, compoundYield 55%

Procedure

The title compound was synthesised according to Example 4 from 1-(3-Methyl-pyrazin-2-yl)-ethanone and HBr/bromine in 55% yield as grey solid. MS (m/e): 215.0 (M+H, 100%).

Sources & evidence

ORD record: ord-a7e25a86eb764f3d82d03a5985b63516
Source dataset: uspto-grants-2007_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07253197B2

Reaction notes

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