HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Ethylamino-5-(2-oxo-pyrrolidin-1-yl)-benzoic acid → [(2R,3S)-3-({1-[3-Ethylamino-5-(2-oxo-pyrrolidin-1-yl)-phenyl]-methanoyl}-amino)-2-hydroxy-4-phenyl-butyl]-carbamic acid benzyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Ethylamino-5-(2-oxo-pyrrolidin-1-yl)-benzoic acid | HCID 69357754 | — |
| Reactant | phenylmethyl [(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]carbamate hydrochloride | HCID 69358558 | — |
| Product | [(2R,3S)-3-({1-[3-Ethylamino-5-(2-oxo-pyrrolidin-1-yl)-phenyl]-methanoyl}-amino)-2-hydroxy-4-phenyl-butyl]-carbamic acid benzyl ester | HCID 69356635 | — |
Reaction Steps
Description 106 was prepared in an analogous manner to Description 105 from 3-(2-oxo-pyrrolidin-1-yl)-5-pentyloxy-benzoic acid hydrochloride (D104) and 3-ethylamino-5-(2-oxo-pyrrolidin-1-yl)-benzoic acid (A31).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07253198B2 |
| Source dataset | uspto-grants-2007_08 |
| ORD ID | ord-cb9efeb4c0d849728c9561aaae1ed092 |
| Source note | uspto-grants-2007_08 |