HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(2-Oxo-pyrrolidin-1-yl)-5-isopropylamino-benzoic acid hydrochloride → [(2R,3S)-3-({1-[3-Isopropylamino-5-(2-oxo-pyrrolidin-1-yl)-phenyl]-methanoyl}-amino)-2-hydroxy-4-phenyl-butyl]-carbamic acid benzyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(2-Oxo-pyrrolidin-1-yl)-5-isopropylamino-benzoic acid hydrochloride | HCID 69357748 | — |
| Reactant | phenylmethyl [(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]carbamate hydrochloride | HCID 69358558 | — |
| Product | [(2R,3S)-3-({1-[3-Isopropylamino-5-(2-oxo-pyrrolidin-1-yl)-phenyl]-methanoyl}-amino)-2-hydroxy-4-phenyl-butyl]-carbamic acid benzyl ester | HCID 69357723 | — |
Reaction Steps
Description 107 was prepared in an analogous manner to Description 105 from 3-(2-oxo-pyrrolidin-1-yl)-5-isopropylamino-benzoic acid hydrochloride (A44) and ((2R,3S)-3-amino-2-hydroxy-4-phenyl-butyl)-carbamic acid benzyl ester (D104).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07253198B2 |
| Source dataset | uspto-grants-2007_08 |
| ORD ID | ord-f9074b248c9f4bc4a2c1e0896337a9b9 |
| Source note | uspto-grants-2007_08 |