Monobenzone → HCID 19261665, compound

HRID 853146Notes

Reaction equation

HRID 853146 reaction equation
[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][C:12]([OH:15])=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Br[CH2:17][C:18]([O:20][CH3:21])=[O:19].C(=O)([O-])[O-].[Cs+].[Cs+]>>[CH3:21][O:20][C:18](=[O:19])[CH2:17][O:15][C:12]1[CH:11]=[CH:10][C:9]([O:8][CH2:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)=[CH:14][CH:13]=1

Participants

4

Reactant 3

HCID 7638MonobenzoneHCID 10796Cesium carbonateHCID 60984Methyl bromoacetate

Product 1

HCID 19261665HCID 19261665, compound

Procedure

In analogy to the procedure described in Example 1b), the alkylation of 4-benzyloxy-phenol with methyl bromoacetate using cesium carbonate as the base yielded the (4-benzyloxy-phenoxy)-acetic acid methyl ester as white crystals; MS: m/e=272 (M)+.

Sources & evidence

ORD record
ord-479540d329604a8585ada0645ed69a97
Source dataset
uspto-grants-2007_08
Patent number
US07253318B2

Reaction notes

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