3-Tetradecylthioacetylamino-2-tetradecylthioacetylthio-1-triphenylmethyloxypropane → 3-Tetradecylthioacetylamino-2-tetradecylthioacetylthiopropan-1-ol

HRID 853205Notes

Reaction equation

HRID 853205 reaction equation
[CH2:1]([CH2:15][C:16]([NH:18][CH2:19][CH2:20][CH:21]([S:42][C:43](=[S:59])[CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH2:49][CH2:50][CH2:51][CH2:52][CH2:53][CH2:54][CH2:55][CH2:56][CH2:57][CH3:58])[O:22]C(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)=[S:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14]>CCOCC.Cl>[CH2:1]([CH2:15][C:16]([NH:18][CH2:19][CH2:20][CH:21]([S:42][C:43](=[S:59])[CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH2:49][CH2:50][CH2:51][CH2:52][CH2:53][CH2:54][CH2:55][CH2:56][CH2:57][CH3:58])[OH:22])=[S:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14]

Participants

4

Reactant 1

HCID 866032133-Tetradecylthioacetylamino-2-tetradecylthioacetylthio-1-triphenylmethyloxypropane

Product 1

HCID 866032123-Tetradecylthioacetylamino-2-tetradecylthioacetylthiopropan-1-olYield 52%

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidSolventHCID 3283Diethyl EtherSolvent

Procedure

3-tetradecylthioacetylamino-2-tetradecylthioacetylthio-1-triphenylmethyloxy-propane (example 20d) (187 mg, 0.21 mmol) was dissolved in ether saturated with gaseous hydrochloric acid (12 ml). The reaction medium was stirred at room temperature for 20 hours. The precipitate which formed was filtered and washed with diethyl ether to give the desired compound in the form of a white powder.

Workup

  1. customThe precipitate which formed
  2. filtrationwas filtered
  3. washwashed with diethyl ether

Sources & evidence

ORD record
ord-58f0c66fbea140fea729ec4cd5f0685c
Source dataset
uspto-grants-2007_08
Patent number
US07253296B2

Reaction notes

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