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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 853468Generated: October 30, 2026

HCID 22936266, compound → HCID 22936256, compound

https://huagongshe.com/reaction/853468

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 22936266HCID 22936266—
SolventPyridineHCID 1049—
SolventAcetic AnhydrideHCID 7918—
ProductHCID 22936256HCID 2293625637.6%

Reaction Steps

After dissolving N-[4-(6-aminomethyl-7-methoxy-quinolin-4-yloxy)phenyl]-N′-phenylurea trifluoroacetate (40 mg) in pyridine (1.0 ml) and acetic anhydride (1.0 ml), the solution was stirred overnight at room temperature. The reaction solution was concentrated under reduced pressure and the obtained crude product was crystallized with ethyl acetate to obtain the title compound (13 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07253286B2
Source datasetuspto-grants-2007_08
ORD IDord-b1d7857e10074d628b9a132a6766357f
Source noteuspto-grants-2007_08