HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → HCID 58931434, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | 4-Fluorophenyl isocyanate | HCID 70955 | — |
| Reactant | HCID 58931477 | HCID 58931477 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 58931434 | HCID 58931434 | — |
Reaction Steps
After adding toluene (1 ml), acetonitrile (0.5 ml) and 4-fluorophenyl isocyanate (0.03 ml) to 4-(6-phenyl-furo[2.3-d]pyrimidin-4-yloxy)phenylamine (40 mg), the mixture was heated to reflux for 30 minutes. After cooling, the precipitated crystals were filtered out and washed with toluene to obtain the title compound (42 mg) as light yellow crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07253286B2 |
| Source dataset | uspto-grants-2007_08 |
| ORD ID | ord-34d9583d4c6c428b8605562fb1d83982 |
| Source note | uspto-grants-2007_08 |