Aluminium lithium hydride → HCID 22935657, compound

HRID 853742Notes

Reaction equation

HRID 853742 reaction equation
[CH2:1]([CH:3]1[C:8]2([C:13](=[O:14])[CH2:12][CH2:11][CH2:10][CH2:9]2)[CH:7]([CH3:15])[CH:6]=[CH:5][CH2:4]1)[CH3:2].[H-].[H-].[H-].[H-].[Li+].[Al+3]>>[CH2:1]([CH:3]1[C:8]2([CH:13]([OH:14])[CH2:12][CH2:11][CH2:10][CH2:9]2)[CH:7]([CH3:15])[CH:6]=[CH:5][CH2:4]1)[CH3:2]

Participants

3

Reactant 2

HCID 21226445Aluminium lithium hydrideHCID 22935664HCID 22935664, compound

Product 1

HCID 22935657HCID 22935657, compoundYield 92%

Procedure

11-Ethyl-7-methylspiro[5,5]undec-8-en-1-one was reduced with LiAlH4 according to the general procedure (example 2, procedure 3) to give the title compound in 92% yield, as a 4:1 mixture of isomers. The crude product was purified by bulb-to-bulb distillation (B.p.=102° C./0.03 mbar).

Sources & evidence

ORD record
ord-297ffc2a6c5c472a97ffd599854ce1a1
Source dataset
uspto-grants-2007_08
Patent number
US07256170B2

Reaction notes

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