3,4,5-Trimethoxybenzaldehyde → HCID 85326795, compound

Participants

Reaction Steps

The title compound was prepared from a mixture of 2,5-bis(2,2,2-trifluoroethoxy)acetophenone (200 mg, 0.633 mmol) and 3,4,5-trimethoxybenzaldehyde (124 mg, 0.633 mmol) similar to Example 6 and isolated as a bright yellow solid (120 mg, 38%), 1H NMR (CDCl3): 7.65 (d, J=15.6 Hz, 1H), 7.42 (d, J=15.6 Hz, 1H), 7.34 (d, J=3.3 Hz, 1H), 7.12 (dd, J=3.3, 9.0 Hz, 1H), 6.93 (d, J=9.0 Hz, 1H), 6.85 (s, 2H), 4.48-4.34 (m, 4H), 3.90 (d, J=1.8 Hz, 9H).

Provenance & Evidence