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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 854284Generated: October 31, 2026

Hydrochloric Acid → HCID 131726552, compound

https://huagongshe.com/reaction/854284

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 69156110HCID 69156110—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 131726552HCID 131726552—

Reaction Steps

A solution of (3R,7R)-4-[(3R)-3-[(tert-butoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoyl]-3,7-dimethyl-1,4-diazepan-2-one (175 mg, 0.38 mmol) in 4 mL of 4N hydrogen chloride in dioxane (4 mL, 4N) was stirred for 2 h and concentrated. The residue was dried under vacuum overnight to yield the title compound as a white solid. MS 358.2 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07259160B2
Source datasetuspto-grants-2007_08
ORD IDord-75e1798cc571455e86e336cc57dedd1d
Source noteuspto-grants-2007_08