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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 854348Generated: October 30, 2026

Thiazole-4-carboxaldehyde → 2-[N-(1,3-Thiazol-4-ylmethylene)amino]-3-(pyridin-2-yl)propionic acid, tert-butyl ester

https://huagongshe.com/reaction/854348

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThiazole-4-carboxaldehydeHCID 2763214—
ReactantTert-butyl 2-amino-3-(pyridin-2-yl)propanoateHCID 83225413—
Product2-[N-(1,3-Thiazol-4-ylmethylene)amino]-3-(pyridin-2-yl)propionic acid, tert-butyl esterHCID 86596693—

Reaction Steps

Prepared in a similar manner to that described for Intermediate 1, replacing 2-amino-4-methyl-pentanoic acid tert-butyl ester, hydrochloride with 2-amino-3-(2-pyridyl) propionic acid, tert-butyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07259163B2
Source datasetuspto-grants-2007_08
ORD IDord-380345d722db4edf8ab11345a681b4f1
Source noteuspto-grants-2007_08