Benzenamine, 4-(4-morpholinyl)- → HCID 58934272, compound

HRID 854446Notes

Reaction equation

HRID 854446 reaction equation
[O:1]1[CH2:6][CH2:5][N:4]([C:7]2[CH:13]=[CH:12][C:10]([NH2:11])=[CH:9][CH:8]=2)[CH2:3][CH2:2]1.[Cl:14][C:15]1[CH:20]=[N:19][CH:18]=[C:17](Cl)[N:16]=1>>[Cl:14][C:15]1[N:16]=[C:17]([NH:11][C:10]2[CH:12]=[CH:13][C:7]([N:4]3[CH2:3][CH2:2][O:1][CH2:6][CH2:5]3)=[CH:8][CH:9]=2)[CH:18]=[N:19][CH:20]=1

Participants

3

Reactant 2

HCID 75655Benzenamine, 4-(4-morpholinyl)-HCID 785042,6-Dichloropyrazine

Product 1

HCID 58934272HCID 58934272, compoundYield 37%

Procedure

In a procedure analogous to example 1, reaction of 4-morpholinoaniline (2.15 g, 12.1 mmol) and 2,6-dichloropyrazine (0.756 g, 5.03 mmol) furnished the product (0.54 g, 37%).

Sources & evidence

ORD record
ord-bd296db5baa64124bc16f921b00f5f6f
Source dataset
uspto-grants-2007_08
Patent number
US07259179B2

Reaction notes

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