HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Dichloropyrazine → 6-Chloro-N-[(1S)-1-(4-methoxyphenyl)ethyl]pyrazin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Dichloropyrazine | HCID 78504 | — |
| Reactant | 1-(4-Methoxyphenyl)ethanamine | HCID 238181 | — |
| Product | 6-Chloro-N-[(1S)-1-(4-methoxyphenyl)ethyl]pyrazin-2-amine | HCID 58717083 | 79% |
Reaction Steps
In a procedure analogous to example 1, reaction of 4-methoxy-α-methyl-benzylamine (700 mg, 4.6 mmol) and 2,6-dichloropyrazine (626 mg, 4.2 mmol) furnished the product (873 mg, 79%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07259179B2 |
| Source dataset | uspto-grants-2007_08 |
| ORD ID | ord-1f0f5c035df24d6a90da190d1397fd9c |
| Source note | uspto-grants-2007_08 |