Hydrochloric Acid → HCID 10195159, compound

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Reaction Steps

To a solution of {4-[4-Ethyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethoxy]-3-methyl-phenoxy}-acetic acid ethyl ester (80 mg) in THF (1 mL) is added LiOH (1.0 M, 1.0 mL), after 1 hr, acidified by 5 N HCl and extracted with ethyl, dried over sodium sulfate. Concentration gave the title acid compound (80 mg). MS (ES): 452.03 (M++1), the structure is also confirmed by proton NMR.

Provenance & Evidence