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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 854636Generated: October 30, 2026

2-Naphthalenecarboxaldehyde → 4-Iodomethyl-5-methyl-2-naphthalen-2-yloxazole

https://huagongshe.com/reaction/854636

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-NaphthalenecarboxaldehydeHCID 6201—
Reactant2-Oxime 2,3-butanedioneHCID 6398969—
Reactant4-Iodomethyl-5-phenyl-2-p-tolyloxazoleHCID 57434504—
Product4-Iodomethyl-5-methyl-2-naphthalen-2-yloxazoleHCID 21074268—

Reaction Steps

Analogously to the building block synthesis of 4-iodomethyl-5-phenyl-2-p-tolyloxazole, butane-2,3-dione-2-oxime and naphthalene-2-carbaldehyde gave 5-methyl-4-iodomethyl-2-naphthalen-2-yloxazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07259177B2
Source datasetuspto-grants-2007_08
ORD IDord-3669f51637864241a313163f01b1b3b5
Source noteuspto-grants-2007_08