HRID854646

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：Cc1ccc(-c2nc(CO[C@@H]3CCC[C@H](COC(C)(C)C(=O)OC(C)(C)C)C3)c(C)o2)cc1

HCID69242284

未命名化合物

PRODUCTS

生成物

结构：Cc1ccc(-c2nc(CO[C@@H]3CCC[C@H](COC(C)(C)C(=O)O)C3)c(C)o2)cc1

HCID68863732

未命名化合物

收率 37.6%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6422

未命名化合物

PROCEDURE

实验过程

200 mg of tert-butyl 2-[cis-3-(5-methyl-2-p-tolyloxazol-4-ylmethoxy)cyclo-hexylmethoxy]-2-methylpropionate are stirred in 2 ml of trifluoroacetic acid for 1 h. The solution is concentrated completely and purified by flash chromatography (heptane/ethyl acetate 5/1) giving 66 mg of 2-[cis-3-(5-methyl-2-p-tolyloxazol-4-ylmethoxy)cyclohexylmethoxy]-2-methylpropionic acid.

WORKUP

后处理

concentrationThe solution is concentrated completely
custompurified by flash chromatography (heptane/ethyl acetate 5/1)