反应详情

A solution of 0.90 g (2.39 mmol) 2-{1-[2-(4-benzyloxy-phenyl)-oxazol-4-ylmethyl]-1H-imidazol-2-yl}-ethanol in 60 ml THF was hydrogenated for 2 hours over 250 mg 10% Pd/C at ambient temperature and pressure. After filtration, the solvent was evaporated to leave 0.55 g (80%) 4-{4-[2-(2-hydroxy-ethyl)-imidazol-1-ylmethyl]-oxazol-2-yl}-phenyl as light yellow crystals.

1. filtrationAfter filtration
2. customthe solvent was evaporated
3. customto leave 0.55 g (80%) 4-{4-[2-(2-hydroxy-ethyl)-imidazol-1-ylmethyl]-oxazol-2-yl}-phenyl as light yellow crystals