4-Chlorobenzoyl chloride → HCID 69517098, compound

Participants

Reaction Steps

To a solution of the title product of Example 130 Step 1 (150 mg, 0.397 mmole) in 5 mL of pyridine was added a solution of 4-chlorobenzoyl chloride (90 mg, 0.51 mmole) in 1 mL of DCM. The mixture was stirred for 2 h, and 750 mg of Tris amine resin was added. After stirring overnight, the mixture was filtered and concentrated to give the title compound, which was used as is for the next step.

Provenance & Evidence