Sodium Hydroxide → HCID 69517256, compound

Participants

Reaction Steps

A solution of 47.6 mg (0.119 mmole) of 6-chloro-7-(4-ethylphenoxy)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid in 1.5 mL of ethanol was treated with 1.18 mL of 0.1008N NaOH. The resultant mixture was lyophilized to provide 51 mg (quant.) of an off-white solid: 1H NMR (CD3OD/400 MHz) 1.25 (t, 3H, J=7.7 Hz), 2. 68 (q, 2H, J=7.7 Hz), 5.79 (q, 1H, J=7.2 Hz), 6.92 (d, 2H, J=8.6 Hz), 7.25 (d, 2H, J=8.6 Hz), 7.37 (m, 2H); MS (ES+) 399 (M+1, 100).

Provenance & Evidence