Sodium Hydroxide → HCID 69516435, compound

Participants

Reaction Steps

To the solution of 0.785 g (2.51 mm) of 6-ethyl-7-methoxy-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid in 20 mL of ethanol was added 24.9 mL of 0.1008 N aqueous solution of sodium hydroxide. The resulting solution was stirred at room temperature for half an hour. The volatiles were removed. The residue was dissolved in 20 mL of water. The resulting solution was frozen and lyophilized to give a light yellow solid. LC-MS (ES−) 301 (M−H, 100). HRMS (ES−) m/z calcd for (M−1; C14H12F3O4) 301.0790, found 301.0810.

Provenance & Evidence