Sodium Hydroxide → HCID 69516934, compound

Participants

Reaction Steps

A solution of 7-(4-ethylphenoxy)-8-methyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid 40.3 mg (0.107 mmole) in 2.0 mL of ethanol was treated with 1.057 mL of 0.1008N NaOH. The resultant mixture was lyophilized to provide a quantitative yield of a yellow solid: 1H NMR (CD3OD/400 MHz) 1.21 (t, 3H, J=7.6 Hz), 2.12 (s, 3H), 2.61 (q, 2H, J=7.6 Hz), 5.87 (q, 1H, J=7.2 Hz), 6.38 (d, 1H, J=8.0 Hz), 6.84 (d, 2H, J=8.0 Hz), 7.00 (d, 1H), J=8.0 Hz), 7.17 (d, 2H, J=8.0 Hz), 7.40 (s, 1H).

Provenance & Evidence