HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → HCID 69515484, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | HCID 69515909 | HCID 69515909 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 69515484 | HCID 69515484 | — |
Reaction Steps
The procedure is as in Step A of Example 3 but replacing the ammonia gas with 2M dimethylamine in THF and 3-{4-[5,5-dioxo-2,3-dihydro-1H-pyrrolo[2,1-c][1,2,4]benzothiadiazin-7-yl)oxy]phenyl}propanoic acid by the compound obtained in Step B. Purification is carried out by chromatography on a silica column, eluting with a mixture of CH2Cl2/MeOH 99/1, followed by crystallisation from water.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07262190B2 |
| Source dataset | uspto-grants-2007_08 |
| ORD ID | ord-6636c1819d8c49f09dec171cd1e37a47 |
| Source note | uspto-grants-2007_08 |