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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 855665Generated: October 28, 2026

Tetrahydrofuran → HCID 178526743, compound

https://huagongshe.com/reaction/855665

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactant4,6-Dichloro-5-nitropyrimidineHCID 20312—
ReactantHCID 178418806HCID 178418806—
ProductHCID 178526743HCID 178526743—

Reaction Steps

To a solution of 4,6-dichloro-5-nitro-pyrimidine (100 mg, 0.52 mmol) in anhydrous THF (2 mL) was added aminopyrazole (76 mg, 0.62 mmol). The solution was stirred at RT for 2 hrs and was filtered via short silica gel column. The filtrate that contained product and the unreacted starting pyrrimidine was concentrated under vacuum. The resulting residue was used directly without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07262200B2
Source datasetuspto-grants-2007_08
ORD IDord-eb0861f658c64e0dbed2f7cb1a384254
Source noteuspto-grants-2007_08