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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 856737Generated: October 30, 2026

Thionyl Chloride → HCID 18670786, compound

https://huagongshe.com/reaction/856737

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThionyl ChlorideHCID 24386—
Reactant[1-(2-Methoxyethyl)-1H-imidazol-5-yl]methanolHCID 18670918—
ProductHCID 18670786HCID 18670786—

Reaction Conditions

Temperature80 °C

Reaction Steps

5-hydroxymethyl-1-(2-methoxyethyl)imidazole (2.8 g) was added to thionyl chloride (8.4 ml), and the mixture was stirred for 1 hour at 80° C. The solvent was removed under reduced pressure, and the obtained residue was washed with ethyl acetate, to give 5-chloromethyl-1-(2-methoxyethyl)imidazole hydrochloride (3.2 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07262185B2
Source datasetuspto-grants-2007_08
ORD IDord-35523e6fbde34cf2bb7fd1665815d0e8
Source noteuspto-grants-2007_08