Thionyl Chloride → HCID 22938853, compound

Participants

Reaction Conditions

Reaction Steps

To 1-cyclopropylmethyl-2-hydroxymethylimidazole (2.50 g) was added thionyl chloride (25 ml) at 0° C., and the mixture was heated for 30 minutes under nitrogen atmosphere at 90° C. The mixture was allowed to be at room temperature, the solvent was distilled off under reduced pressure and the obtained solid was washed with ethyl acetate, to give 2-chloromethyl-1-cyclopropylmethylimidazole hydrochloride. (2.96 g) as brown crystals.

Provenance & Evidence