Thionyl Chloride → HCID 69521313, compound

Participants

Reaction Conditions

Reaction Steps

To 1-(2-butyl)-2-hydroxymethylimidazole (2.70 g) was added thionyl chloride (27 ml) at 0° C., and the mixture was heated for 30 minutes under nitrogen atmosphere at 90° C. The mixture was allowed to be at room temperature. The solvent was distilled off under reduced pressure, and the obtained residue was recrystallized from ethyl acetate, to give 1-(2-butyl)-2-chloromethylimidazole hydrochloride (3.09 g) as brown crystals.

Provenance & Evidence