Thionyl Chloride → HCID 22938760, compound

Participants

Reaction Conditions

Reaction Steps

To 2-hydroxymethyl-1-pentylimidazole (3.8 g) was added thionyl chloride (38 ml) at 0° C., and the mixture was heated for 30 minutes under nitrogen atmosphere at 90° C. The mixture was allowed to be at room temperature. The solvent was distilled off under reduced pressure and the obtained residue was recrystallized from methanol-ethyl acetate, to give 2-chloromethyl-1-pentylimidazole hydrochloride (3.00 g) as brown crystals.

Provenance & Evidence