Thionyl Chloride → HCID 22938536, compound

Participants

Reaction Conditions

Reaction Steps

To 4-hydroxymethyl-1-propylimidazole (2.5 g), thionyl chloride (25 ml) was added by portions at 0° C., and the mixture was heated for 30 minutes under nitrogen atmosphere at 90° C. The mixture was allowed to be at room temperature. The solvent was distilled off under reduced pressure and the obtained residue was dissolved in methanol. The solvent was distilled off again under reduced pressure, to give 4-chloromethyl-1-propylimidazole hydrochloride (3.47 g) as brown oil.

Provenance & Evidence