P-Anisidine → HCID 21862856, compound

HRID 856810Notes

Reaction equation

HRID 856810 reaction equation
[CH3:1][S:2]([C:5]1[CH:12]=[CH:11][C:8]([CH:9]=O)=[CH:7][CH:6]=1)(=[O:4])=[O:3].[CH3:13][O:14][C:15]1[CH:21]=[CH:20][C:18]([NH2:19])=[CH:17][CH:16]=1>C(O)C>[CH3:13][O:14][C:15]1[CH:21]=[CH:20][C:18]([N:19]=[CH:9][C:8]2[CH:11]=[CH:12][C:5]([S:2]([CH3:1])(=[O:4])=[O:3])=[CH:6][CH:7]=2)=[CH:17][CH:16]=1

Participants

4

Reactant 2

HCID 7732P-AnisidineHCID 2203764-(Methylsulfonyl)benzaldehyde

Product 1

HCID 21862856HCID 21862856, compoundYield 95%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

1.00 g (5.4 mmol) of 4-methylsulfonylbenzaldehyde and 0.67 g (5.4 mmol) of 4-methoxyaniline were dissolved in 15 ml of ethanol, and the solution was heated under reflux for 1 hour. At the end of this time, the reaction solution was cooled to room temperature, and the crystals which precipitated were collected by filtration and washed with ethanol, to give 1.48 g (yield 95%) of the title compound as slightly yellow prismatic crystals.

Workup

  1. temperaturethe solution was heated
  2. temperatureunder reflux for 1 hour
  3. customthe crystals which precipitated
  4. filtrationwere collected by filtration
  5. washwashed with ethanol

Sources & evidence

ORD record
ord-d0fa0c38e45549d0b64364340fd7667e
Source dataset
uspto-grants-2006_12
Patent number
USRE039420E1

Reaction notes

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