HuagongsheHuagongshe Chemistry Print Report · For research reference only
2',4'-Bis(trifluoromethyl)acetophenone → 2,4-Bis(trifluoromethyl)phenacyl bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2',4'-Bis(trifluoromethyl)acetophenone | HCID 2736093 | — |
| Reactant | 2-Bromo-1-(2,5-dichlorophenyl)ethanone | HCID 2756907 | — |
| Product | 2,4-Bis(trifluoromethyl)phenacyl bromide | HCID 2778777 | 63% |
Reaction Steps
This compound was prepared from 1-[2,4-bis(trifluoromethyl)phenyl]ethanone (5.0 g, 19.52 mmol) in the manner described for 2-bromo-1-(2,5-dichlorophenyl)ethanone, affording 4.12 g (63%) of a white solid. 1H-NMR (DMSO-d6) δ 8.28 to 8.16 (m, 3H), 4.98 (s, 2H);
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07144885B2 |
| Source dataset | uspto-grants-2006_12 |
| ORD ID | ord-02b33a90e2ef4adbb2d9313e64b350a2 |
| Source note | uspto-grants-2006_12 |