HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 856965Generated: October 26, 2026
Ethyl bromoacetate → Ethyl (3,5-dichloro-4-formylphenoxy)acetate
https://huagongshe.com/reaction/856965
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethyl bromoacetate | HCID 7748 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2,6-Dichloro-4-hydroxybenzaldehyde | HCID 528382 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | Ethyl (3,5-dichloro-4-formylphenoxy)acetate | HCID 71373969 | — |
Reaction Steps
A mixture of 2.87 g (15 mmol) A1, 2.76 g (16.5 mmol) ethyl bromoacetate and 2.90 g (21 mmol) potassium carbonate in 50 ml dry acetone were stirred for 3 h at 60° C. After filtration and removal of the solvent the residue was purified by column chromatography on Silica (ethyl acetate/methanol 100:2). Yield: 3.5.5 g (86 %) A2, colorless solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07144889B2 |
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| Source dataset | uspto-grants-2006_12 |
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| ORD ID | ord-6f5b0045d096459187a14b2011eb52ff |
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| Source note | uspto-grants-2006_12 |
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