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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 857079Generated: October 28, 2026

Trifluoroacetic anhydride → HCID 21866554, compound

https://huagongshe.com/reaction/857079

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic anhydrideHCID 9845—
Reactant3-Chloro-2-cyanothiopheneHCID 2757438—
Reactant3-chlorothiophene-2-carboxamideHCID 2808088—
Reactant5-(Aminomethyl)-3-methyl-2-thiophenecarbonitrileHCID 21866465—
ProductHCID 21866554HCID 21866554—

Reaction Steps

This compound was prepared in analogy to 5-aminomethyl-3-methylthiophene-2-carbonitrile, preparing the 3-chloro-2-cyanothiophene used by dehydration of 3-chlorothiophene-2-carboxamide with trifluoroacetic anhydride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07144902B1
Source datasetuspto-grants-2006_12
ORD IDord-3f5fdab5cee848afbd7f4309327dd089
Source noteuspto-grants-2006_12