HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 3-[(1-propylbutyl)sulfonyl]alanine HCl salt
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | methyl N-acetyl-3-[(1-propylbutyl)sulfonyl]alaninate | HCID 86589164 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 3-[(1-propylbutyl)sulfonyl]alanine HCl salt | HCID 86589165 | — |
Reaction Steps
Methyl N-acetyl-3-[(1-propylbutyl)sulfonyl]alaninate (LXXXII, 9.2 g) in acetic acid (50 ml) and concentrated hydrochloric acid (50 ml). The mixture is refluxed for 4 hours then concentrated under reduced pressure. The residue is chased with toluene (2×) then vacuum dried overnight to give 3-[(1-propylbutyl)sulfonyl]alanine hydrochloride salt (LXXXIII).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07144897B2 |
| Source dataset | uspto-grants-2006_12 |
| ORD ID | ord-2f5174ef05fb455c97f49d434e146a57 |
| Source note | uspto-grants-2006_12 |