Hydrochloric Acid → HCID 68610371, compound

Participants

Reaction Steps

N1-{(1S,2R)-N-[(t-butyloxy)carbonyl]-1-(3,5-difluorobenzyl)-3-[(3-ethylbenzyl)-amino]-2-hydroxypropyl}-N2-(4-methoxybenzoyl)-3-[(1-propylbutyl)sulfonyl]-D,L-alaninamide, (LXXXVIII, 114 mg, 0.14 mmole) in hydrochloric acid (4 N, 1 ml) in dioxane. After stirring for 10 minutes at 20–25°, the solvent is removed under reduced pressure to give N1-{(1S,2R)-1-(3,5-difluorobenzyl)-3-[(3-ethylbenzyl)amino]-2-hydroxypropyl}-N2-(4-methoxybenzoyl)-3-[(1-propylbutyl)sulfonyl]-D,L-alaninamide hydrochloride,

Provenance & Evidence