HuagongsheHuagongshe Chemistry Print Report · For research reference only
{2-Fluoro-5-[6-(1-methanesulfonyl-1-methyl-ethyl)-quinolin-8-yl]-phenyl}-methanol → 2-Fluoro-5-[6-(1-methanesulfonyl-1-methyl-ethyl)-quinolin-8-yl]-benzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | {2-Fluoro-5-[6-(1-methanesulfonyl-1-methyl-ethyl)-quinolin-8-yl]-phenyl}-methanol | HCID 21865592 | — |
| Solvent | 4-Fluoro-3-(hydroxymethyl)benzeneboronic acid | HCID 21865588 | — |
| Product | 2-Fluoro-5-[6-(1-methanesulfonyl-1-methyl-ethyl)-quinolin-8-yl]-benzaldehyde | HCID 21865564 | — |
Reaction Steps
Prepared according to the oxidation procedure described in Quinoline 14 (Step 1) but using the {2-fluoro-5-[6-(1-methanesulfonyl-1-methyl-ethyl)-quinolin-8-yl]-phenyl)}-methanol from Step 2 as the starting material.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07144896B2 |
| Source dataset | uspto-grants-2006_12 |
| ORD ID | ord-1baa6525ee1f4bedbcb6b4a42f2e0bed |
| Source note | uspto-grants-2006_12 |